Microfiltration Membrane

‌Working Principle: 




Microfiltration membranes are filtration membranes with pore sizes ranging from 0.1 to 1 micron, mainly used to separate suspended particles, bacteria, and macromolecular colloids from liquids. Microfiltration operates through a sieving mechanism that allows large molecules and dissolved solids (e.g., inorganic salts) to pass through while retaining larger suspended particles and microorganisms. The operating pressure of microfiltration membranes generally ranges between 0.3 and 7 bar, making them suitable for various liquid treatment applications.



Features of Microfiltration Membranes:





Diverse Product Options: Available in standard, irradiated, irradiation-compatible, and autoclave-sterilizable types to meet different application needs.

Various Membrane Fiber Sizes: Multiple fiber inner diameters (0.5, 1.0, 1.5 mm) and pore sizes (3 kD-750 kD, 0.1-0.65 μm) to accommodate different filtration requirements.


High Hydrophilicity and High Throughput: Membranes have good hydrophilicity and high flux, significantly improving processing efficiency.

Biological Safety: Free from animal-derived components, with low bioburden, meeting the stringent requirements of the biopharmaceutical industry.

High Reliability and Biocompatibility: 100% integrity-tested and produced in C-class cleanrooms, with membrane housing material meeting USP Class VI standards, ensuring no particle shedding and excellent chemical compatibility.

High Mechanical Strength and Long Process Life: The product has high mechanical strength and long service life, suitable for extended process operations.

High Solid Content Fluid Handling: Capable of handling high-solid-content fluids with strong flexibility, ideal for separating and purifying complex samples.

Excellent Separation Selectivity and High Product Yield: Low protein binding rate, ensuring high product yield, particularly in critical purification steps of biopharmaceuticals.




Applications:





Monoclonal Antibody Clarification and Concentration: Used for the separation, clarification, and concentration of monoclonal antibodies in biopharmaceuticals.

Plasmid Concentration and Washing: Suitable for plasmid DNA concentration and washing processes.

Suspended Solids Removal: Removes solid particles from suspensions, applicable in various biological and industrial applications.

Vaccine Concentration and Purification: Used for the concentration and purification of vaccines, ensuring high purity and efficient separation.

Virus Concentration, Purification, and Removal: Applied in the concentration, purification, and removal of viruses, particularly in the biopharmaceutical industry.

Bacteria and Pyrogen Removal: Ideal for removing bacteria and pyrogens, enhancing the safety of the final product.

Plasma Purification and Concentration: Used in the purification and concentration steps during plasma preparation.


Pyrogen Removal from Buffers: Removes pyrogens from buffers, ensuring product purity and safety.

Cell Harvesting and Clarification: Suitable for cell harvesting and clarification in cell culture processes.

Colloidal Suspension Concentration and Washing: Applied in the concentration and washing of colloidal suspensions.

Continuous Buffer Exchange and Perfusion of Cell Cultures: Supports continuous buffer exchange and perfusion operations, improving production efficiency.

Hybridoma Cell Culture Clarification: Used for the clarification of hybridoma cell cultures in biopharmaceuticals.

Liposome Purification and Lysate Clarification: Applied for liposome purification and lysate clarification.


Mammalian Cell Clarification: Suitable for the clarification of mammalian cell cultures.